Dr Jayaram's current laboratory research program is focused upon translational research towards novel treatments for glaucoma. He has expertise in laboratory models of glaucomatous optic nerve damage and the development of stem cell-based therapies for glaucoma. His clinical research interests focus upon outcomes of glaucoma surgery and clinical trials. He is current co-chair of the Research Management Committee at Moorfields Eye Hospital.
His current research is supported by the Special Trustees of Moorfields Eye Hospital and the Moorfields Eye Charity and the Royal College of Surgeons of Edinburgh. He has received previous grant support from the Medical Research Council, Fight for Sight and the US-UK Fulbright Commission. Dr Jayaram's unique role as a glaucoma clinician-scientist was featured in an article published in the Guardian in October 2016, in order to emphasise the importance of continued funding for eye research in the United Kingdom.